Development and validation of risk prediction model for venous thromboembolism in postpartum women: multinational cohort study.

ABSTRACT:

Objective

 To develop and validate a risk prediction model for venous thromboembolism in the first six weeks after delivery (early postpartum).

Design

 Cohort study.

Setting

 Records from England based Clinical Practice Research Datalink (CPRD) linked to Hospital Episode Statistics (HES) and data from Sweden based registry.

Participants

 All pregnant women registered with CPRD-HES linked data between 1997 and 2014 and Swedish medical birth registry between 2005 and 2011 with postpartum follow-up.

Main outcome measure

 Multivariable logistic regression analysis was used to develop a risk prediction model for postpartum venous thromboembolism based on the English data, which was externally validated in the Swedish data.

Results

 433 353 deliveries w

SUBMITTER: Sultan AA 

PROVIDER: S-EPMC5137302 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature