High-resolution diffusion MRI at 7T using a three-dimensional multi-slab acquisition.

ABSTRACT: High-resolution diffusion MRI can provide the ability to resolve small brain structures, enabling investigations of detailed white matter architecture. A major challenge for in vivo high-resolution diffusion MRI is the low signal-to-noise ratio. In this work, we combine two highly compatible methods, ultra-high field and three-dimensional multi-slab acquisition to improve the SNR of high-resolution diffusion MRI. As each k_z plane is encoded using a single-shot echo planar readout, scan speeds of the proposed technique are similar to the commonly used two-dimensional diffusion MRI. In-plane parallel acceleration is applied to reduce image distortions. To reduce the sensitivity of auto-calibration signal data to subject motion and respiration, several new adaptions of the fast low

SUBMITTER: Wu W 

PROVIDER: S-EPMC5139985 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature