Kidney Function After the First Kidney Stone Event.

ABSTRACT:

Objective

To determine whether there is a persistent decline in kidney function after the first kidney stone event.

Patient and methods

Incident symptomatic stone formers and age- and sex-matched controls underwent 2 study visits 90 days apart to assess kidney function, complete a survey, and have their medical records reviewed. Kidney function was compared between stone formers and controls adjusting for clinical, blood, and urine risk factors.

Results

There were 384 stone formers and 457 controls. At visit 1, a median of 104 days after the stone event, stone formers compared with controls had similar serum creatinine (0.86 vs 0.84 mg/dL; P=.23), higher serum cystatin C (0.83 vs 0.72 mg/L; P<.001), higher urine protein (34.2 vs 19.7 mg/24 h; P<.001) levels, and were

SUBMITTER: Haley WE 

PROVIDER: S-EPMC5140038 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature