Endoscopic sinus surgery improves cognitive dysfunction in patients with chronic rhinosinusitis.

ABSTRACT:

Background

Patients with chronic rhinosinusitis (CRS) have been found to have cognitive deficit, as identified using the Cognitive Failures Questionnaire (CFQ), but the exact etiology of cognitive decline is unknown. In this study we aimed to determine whether improvement in concomitant inflammation and disease burden in CRS, using endoscopic sinus surgery (ESS), improves cognitive deficit. We also sought to identify comorbid conditions that effect improvement likelihood.

Methods

Study participants (n = 247) with and without nasal polyposis (CRSwNP, CRSsNP) were prospectively enrolled in this multi-institutional, observational outcomes study. Pre- and postoperative cognitive dysfunction was evaluated using the CFQ instrument. Quality of life (QOL) and disease burden was also

SUBMITTER: Alt JA 

PROVIDER: S-EPMC5140732 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature