Anhedonia is associated with reduced incentive cue related activation in the basal ganglia.

ABSTRACT: Research has shown that reward incentives improve cognitive control in motivationally salient situations. Much previous work in this domain has focused on incentive cue-related activity in a number of brain regions, including the dorsolateral prefrontal cortex (DLPFC) and striatum. However, the more sustained changes in functional brain activity during task contexts with incentives have been relatively less explored. Here, we examined both the cue-related and sustained effects of rewards (i.e., monetary incentives) on cognitive control, with a particular focus on the roles of the DLPFC and striatum, using a mixed state-item design. We investigated whether variability in a reward-related trait (i.e., anhedonia) would modulate the sustained and/or the cue-related transient aspects of motivat

SUBMITTER: Chung YS 

PROVIDER: S-EPMC5141384 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature