Screening for acute HIV infection in community-based settings: Cost-effectiveness and impact on transmissions.

ABSTRACT:

Objectives

To determine cost-effectiveness of three community-based acute HIV infection (AHI) testing algorithms compared to HIV antibody testing alone by focusing on the potential of averting new infections occurring within a one-year time horizon among men who have sex with men (MSM).

Methods

Data sources for model parameters included actual cost and prevalence data derived from a community-based AHI screening program in San Diego, and published studies. Main outcome measure was costs per infection averted (IA). The lower end of the cost range of discounted lifetime costs of an HIV infection (i.e. $236,948) was used for defining cost-effectiveness.

Results

The most sensitive algorithm for AHI detection, which was based on HIV nucleic acid amplification testing, was

SUBMITTER: Hoenigl M 

PROVIDER: S-EPMC5143169 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature