Impact of Cognitive Function Change on Mortality in Renal Transplant and End-Stage Renal Disease Patients.

ABSTRACT:

Background

Limited evidence from small-scale studies, mainly involving end-stage renal disease (ESRD) patients, suggests that kidney transplantation may improve cognitive function. We examined changes in cognitive function after a kidney transplant and its association with survival in advanced chronic kidney disease (CKD)/ESRD patients.

Methods

In a prospective study design, cognitive performance of 90 patients (50.6 ± 13.1 years, 66.7% men, 27.8% blacks, 76% CKD stages 4-5) was assessed at the respective patients' residences using established neurocognitive tests.

Results

Among the 90 patients, 44 received a kidney transplant (KTx group) while 46 did not (no-KTx group). After a mean follow-up of ∼19 months, there was no significant change in scores for majority of co

SUBMITTER: Sharma A 

PROVIDER: S-EPMC5143182 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature