Efficacy and tolerability of the modified Atkins diet in young children with refractory epilepsy: Indian experience.

ABSTRACT:

Background

The modified Atkins diet (MAD) has been used predominantly in older children, adolescents, and adults. There is a paucity of data on the use of the MAD in refractory epilepsy in young children.

Objectives

This study was planned to evaluate the efficacy and tolerability of the MAD in refractory epilepsy in young children.

Methods

This study recruited children aged 9 months to 3 years with refractory seizures. Children received MAD for 6-month with the on-going anticonvulsant medications being continued unchanged. Reduction in seizure frequency was the primary outcome measure. Adverse effects were also studied.

Results

Thirty-one children with daily seizures were studied with a median age of 18-month (range 9-30 months). West syndrome was the most comm

SUBMITTER: Mehta R 

PROVIDER: S-EPMC5144480 | biostudies-literature | 2016 Oct-Dec

REPOSITORIES: biostudies-literature