Impact of Cigarette Smoking and Smoking Cessation on Life Expectancy Among People With HIV: A US-Based Modeling Study.

ABSTRACT:

Background

 In the United States, >40% of people infected with human immunodeficiency virus (HIV) smoke cigarettes.

Methods

 We used a computer simulation of HIV disease and treatment to project the life expectancy of HIV-infected persons, based on smoking status. We used age- and sex-specific data on mortality, stratified by smoking status. The ratio of the non-AIDS-related mortality risk for current smokers versus that for never smokers was 2.8, and the ratio for former smokers versus never smokers was 1.0-1.8, depending on cessation age. Projected survival was based on smoking status, sex, and initial age. We also estimated the total potential life-years gained if a proportion of the approximately 248 000 HIV-infected US smokers quit smoking.

Results

 Men and women

SUBMITTER: Reddy KP 

PROVIDER: S-EPMC5144729 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature