Low incidence of inbreeding in a long-lived primate population isolated for 75 years.

ABSTRACT:

Abstract

When close relatives mate, offspring are expected to suffer fitness consequences due to inbreeding depression. Inbreeding has previously been quantified in two ways: using a sufficiently large panel of markers or deep and complete pedigrees over several generations. However, the application of both approaches is still limited by the challenge of compiling such data for species with long generation times, such as primates. Here, we assess inbreeding in rhesus macaques living on Cayo Santiago (Puerto Rico), a population genetically isolated since 1938, but descendant of a large set of presumably unrelated founders. Using comprehensive genetic data, we calculated inbreeding coefficients (F) for 2669 individuals with complete three generation pedigrees and 609 individua

SUBMITTER: Widdig A 

PROVIDER: S-EPMC5145906 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature