Markers of kidney disease and risk of subclinical and clinical heart failure in African Americans: the Jackson Heart Study.

ABSTRACT:

Background

African Americans and patients with chronic kidney disease (CKD) are at high risk for clinical heart failure (HF). In this study, we aimed to determine the association of markers of kidney disease with subclinical HF (by echocardiogram) and risk of clinical HF among a large, well-characterized community-based cohort of African American patients. We also examined whether the association of markers of kidney disease with HF was attenuated with adjustment for echocardiographic measures.

Methods

We studied participants in the Jackson Heart Study, a large community-based cohort of African Americans. Estimated glomerular filtration rate (eGFR) and urine albumin:creatinine ratio (ACR) were measured at baseline. We tested the association of eGFR and urine ACR with left ve

SUBMITTER: Bansal N 

PROVIDER: S-EPMC5146707 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature