2014-2015 Influenza Vaccine Effectiveness in the United States by Vaccine Type.

ABSTRACT:

Background

 Circulating A/H3N2 influenza viruses drifted significantly after strain selection for the 2014-2015 vaccines. Also in 2014-2015, the Advisory Committee on Immunization Practices recommended preferential use of live attenuated influenza vaccine (LAIV) over inactivated influenza vaccine (IIV) among children aged 2-8 years.

Methods

 Vaccine effectiveness (VE) across age groups and vaccine types was examined among outpatients with acute respiratory illness at 5 US sites using a test-negative design, that compared the odds of vaccination among reverse transcription polymerase chain reaction-confirmed influenza positives and negatives.

Results

 Of 9311 enrollees with complete data, 7078 (76%) were influenza negative, 1840 (19.8%) were positive for influenza A (A

SUBMITTER: Zimmerman RK 

PROVIDER: S-EPMC5146719 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature