Osmoregulated Chloride Currents in Hemocytes from Mytilus galloprovincialis.

ABSTRACT: We investigated the biophysical properties of the transport mediated by ion channels in hemocytes from the hemolymph of the bivalve Mytilus galloprovincialis. Besides other transporters, mytilus hemocytes possess a specialized channel sensitive to the osmotic pressure with functional properties similar to those of other transport proteins present in vertebrates. As chloride fluxes may play an important role in the regulation of cell volume in case of modifications of the ionic composition of the external medium, we focused our attention on an inwardly-rectifying voltage-dependent, chloride-selective channel activated by negative membrane potentials and potentiated by the low osmolality of the external solution. The chloride channel was slightly inhibited by micromolar concentrations of zin

SUBMITTER: Bregante M 

PROVIDER: S-EPMC5148081 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature