Implantable microcoils for intracortical magnetic stimulation.

ABSTRACT: Neural prostheses that stimulate the neocortex have the potential to treat a wide range of neurological disorders. However, the efficacy of electrode-based implants remains limited, with persistent challenges that include an inability to create precise patterns of neural activity as well as difficulties in maintaining response consistency over time. These problems arise from fundamental limitations of electrodes as well as their susceptibility to implantation and have proven difficult to overcome. Magnetic stimulation can address many of these limitations, but coils small enough to be implanted into the cortex were not thought strong enough to activate neurons. We describe a new microcoil design and demonstrate its effectiveness for both activating cortical neurons and driving behavioral r

SUBMITTER: Lee SW 

PROVIDER: S-EPMC5148213 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature