Genetic determinants of swallowing impairment, recovery and responsiveness to treatment.

ABSTRACT:

Purpose of review

Here we review the latest literature and evidence in the field of genetics and determinants of swallowing and its treatments-specifically, this is a very recent concept in the field of oropharyngeal dysphagia, with only now an emerging research interest in the relationship between our genetic makeup and the effect this has on swallowing function and dysfunction. As such our review will look at preclinical, clinical and hypothesis generating research covering all aspects of the genetics of swallowing, giving new importance to the genotype-phenotype influences pertaining to dysphagia and its recovery.

Recent findings

There appear to be a number of candidate gene systems that interact with swallowing or its neurophysiology, which include brain-derived neurotro

SUBMITTER: Raginis-Zborowska A 

PROVIDER: S-EPMC5148785 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature