Whole-genome sequencing of eight goat populations for the detection of selection signatures underlying production and adaptive traits.

ABSTRACT: The goat (Capra hircus) is one of the first farm animals that have undergone domestication and extensive natural and artificial selection by adapting to various environments, which in turn has resulted in its high level of phenotypic diversity. Here, we generated medium-coverage (9-13×) sequences from eight domesticated goat breeds, representing morphologically or geographically specific populations, to identify genomic regions representing selection signatures. We discovered ~10 million single nucleotide polymorphisms (SNPs) for each breed. By combining two approaches, ZH_p and di values, we identified 22 genomic regions that may have contributed to the phenotypes in coat color patterns, body size, cashmere traits, as well as high altitude adaptation in goat populations. Candida

SUBMITTER: Wang X 

PROVIDER: S-EPMC5150979 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature