Warfarin treatment and risk of stroke among primary care patients with atrial fibrillation.

ABSTRACT:

Objective

Our aim was to study the risk of a first ischaemic stroke (IS) in patients with atrial fibrillation (AF) treated in primary healthcare.

Design

The study population included all adults (n = 11,517), 45 years and older diagnosed with AF, from 75 primary care centres in Sweden between 2001 and 2007. IS was defined as a hospital care event of stroke between 2001 and 2010. Association between incident stroke and warfarin treatment was explored using Cox regression analysis, with hazard ratios (HRs), and 95% confidence intervals (95%CIs). Adjustment was made for age, socioeconomic factors and co-morbidity.

Results

Persistent treatment with warfarin was present among 33.7% of women and 40.0% among men. Persistent warfarin treatment, compared to no persistent treatm

SUBMITTER: Wandell P 

PROVIDER: S-EPMC5152680 | biostudies-literature | 2016 Oct - Dec

REPOSITORIES: biostudies-literature