Prophylactic Antiarrhythmic Drug Therapy in Atrial Fibrillation.

ABSTRACT: In patients with recurrent atrial fibrillation (AF), the hallmark of treatment has been the use of antiarrhythmic drugs (AADs). Goals of therapy include reduction in the frequency and duration of episodes of arrhythmia as well an emerging goal of reducing mortality and hospitalizations associated with AF. Safety and efficacy are important factors when choosing an antiarrhythmic drug for the treatment of AF, hence, if AAD are required for maintenance of sinus rhythm, their safety profi le, together with individual patient characteristics, should be of utmost concern. In the next paragraphs we would like to review some aspects (electrophysiologic effects, metabolism, side effects, current evidence and indication) of the most commonly used AAD for the management of patients with AF, following

SUBMITTER: Rodriguez-Manero M 

PROVIDER: S-EPMC5153102 | biostudies-literature | 2013 Feb-Mar

REPOSITORIES: biostudies-literature