Combined ¹⁸F-FDG-PET and diffusion tensor imaging in mesial temporal lobe epilepsy with hippocampal sclerosis.

ABSTRACT:

Objectives

Several studies using ¹⁸F-fluorodeoxyglucose positron emission tomography (¹⁸F-FDG-PET) or diffusion tensor imaging (DTI) have found both temporal and extratemporal abnormalities in patients with mesial temporal lobe epilepsy with ipsilateral hippocampal sclerosis (MTLE-HS), but data are lacking about the findings of both techniques in the same patients. We aimed to determine whether the extent of ¹⁸F-FDG-PET hypometabolism is related to DTI abnormalities.

Methods

Twenty-one patients with MTLE-HS underwent comprehensive preoperative evaluation; 18 (86%) of these underwent epilepsy surgery. We analyzed and compared the pattern of white matter (WM) alterations on DTI and cortical hypometabolism on ¹⁸F-FDG-PET.

Results</

SUBMITTER: Aparicio J 

PROVIDER: S-EPMC5153605 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature