Ontology highlight
ABSTRACT:
SUBMITTER: Spadoni I
PROVIDER: S-EPMC5153614 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Spadoni Ilaria I Pietrelli Alessandro A Pesole Graziano G Rescigno Maria M
Gut microbes 20161010 6
It has been widely demonstrated that tolerance against gut microbiota is compartmentalized to mucosal sites where microbes mostly reside. How the commensal bacteria are excluded from the entrance into the blood stream via intestinal capillaries that are located beneath the gut epithelium was not clear. We recently described the existence of a new anatomical structure, the 'gut vascular barrier' (GVB), both in murine and human intestines that plays a fundamental role in avoiding indiscriminate tr ...[more]