Analysis of complete genomes of the rubella virus genotypes 1E and 2B which circulated in China, 2000-2013.

ABSTRACT: Rubella viruses of genotypes 1E and 2B are currently the most frequently detected wild-type viruses in the world. Genotype 1E viruses from China have been genetically distinct from genotype 1E viruses found elsewhere, while genotype 2B viruses found in China are not distinguishable from genotype 2B viruses from other areas. Genetic clusters of viruses of both genotypes were defined previously using sequences of the 739-nt genotyping window. Here we report phylogenic analysis using whole genomic sequences from seven genotype 1E and three genotype 2B viruses which were isolated in China between 2000 and 2013 and confirm the subgrouping of current circulating genotypes 1E and 2B viruses. In addition, the whole genomic characterization of Chinese rubella viruses was clarified. The results indi

SUBMITTER: Zhu Z 

PROVIDER: S-EPMC5154293 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature