Cognitive impairment in Parkinson's disease: Association between patient-reported and clinically measured outcomes.

ABSTRACT:

Background

In Parkinson's disease, the association between objective and patient-reported measures of cognitive dysfunction is unknown and highly relevant to research and clinical care.

Objective

To determine which cognitive domain-specific Montreal Cognitive Assessment (MoCA) subscores are most strongly associated with patient-reported cognitive impairment on question 1 (Q1) of the Movement Disorders Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS).

Methods

We analyzed data from 759 PD participants and 481 persons without PD with in a retrospective, cross sectional analysis using data from the NINDS Parkinson's Disease Biomarkers Program (PDBP), a longitudinal, multicenter biomarker study. The relationship between a patient-reported cognitive rating (MDS-

SUBMITTER: Mills KA 

PROVIDER: S-EPMC5154808 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature