Strain-Dependent Transcriptome Signatures for Robustness in Lactococcus lactis.

ABSTRACT: Recently, we demonstrated that fermentation conditions have a strong impact on subsequent survival of Lactococcus lactis strain MG1363 during heat and oxidative stress, two important parameters during spray drying. Moreover, employment of a transcriptome-phenotype matching approach revealed groups of genes associated with robustness towards heat and/or oxidative stress. To investigate if other strains have similar or distinct transcriptome signatures for robustness, we applied an identical transcriptome-robustness phenotype matching approach on the L. lactis strains IL1403, KF147 and SK11, which have previously been demonstrated to display highly diverse robustness phenotypes. These strains were subjected to an identical fermentation regime as was performed earlier for strain MG1363 and co

SUBMITTER: Dijkstra AR 

PROVIDER: S-EPMC5156439 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature