Fatigue and fluid hydration status in multiple sclerosis: A hypothesis.

ABSTRACT:

Background

Fatigue is a prevalent and functionally disabling symptom for individuals living with multiple sclerosis (MS) which is poorly understood and multifactorial in etiology. Bladder dysfunction is another common MS symptom which limits social engagement and quality of life. To manage bladder issues, individuals with MS tend to limit their fluid intake, which may contribute to a low-hydration (LoH) state and fatigue.

Objective

To evaluate the relationship between patient-reported MS fatigue, bladder dysfunction, and hydration status.

Methods

We performed a prospective cross-sectional study in 50 women with MS. Participants submitted a random urine sample and completed several fatigue-related surveys. Using a urine specific gravity (USG) threshold of 1.015, we cla

SUBMITTER: Cincotta MC 

PROVIDER: S-EPMC5156578 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature