Association of Antipsychotic Use With Mortality Risk in Patients With Parkinson Disease.

ABSTRACT:

Importance

As many as 60% of patients with Parkinson disease (PD) experience psychosis, 80% develop dementia, and the use of antipsychotics (APs) in the population with PD is common. The use of APs by patients with dementia in the general population is associated with increased mortality, but whether this risk extends to patients with PD remains unknown.

Objective

To determine whether AP use in patients with PD is associated with increased mortality.

Design, setting, and participants

This retrospective matched-cohort study used data from a Veterans Health Administration database from fiscal years 1999 to 2010 to examine the risk associated with AP use in a cohort of patients with idiopathic PD and recent stable physical health. The rates of 180-day mortality were comp

SUBMITTER: Weintraub D 

PROVIDER: S-EPMC5157923 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature