The association between WNT10A variants and dental development in patients with isolated oligodontia.

ABSTRACT: In this study we aimed to determine the effect of WNT10A variants on dental development in patients with oligodontia. Forty-three (25 boys and 18 girls) individuals were eligible for this study. Stage of development for each present tooth was assessed using the Demirjian method. In case no corresponding tooth was present, regression equations were applied for dental age to be calculated. The ratio between length of root and length of crown was ascertained for each present tooth in all quadrants. All patients were physically examined by a clinical geneticist and DNA analysis of the WNT10A gene was performed. Linear regression models were applied to analyze the association between WNT10A variants and dental age. The same analysis was applied to study the association between WNT10A variants a

SUBMITTER: Dhamo B 

PROVIDER: S-EPMC5159758 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature