Pan- and core- network analysis of co-expression genes in a model plant.

ABSTRACT: Genome-wide gene expression experiments have been performed using the model plant Arabidopsis during the last decade. Some studies involved construction of coexpression networks, a popular technique used to identify groups of co-regulated genes, to infer unknown gene functions. One approach is to construct a single coexpression network by combining multiple expression datasets generated in different labs. We advocate a complementary approach in which we construct a large collection of 134 coexpression networks based on expression datasets reported in individual publications. To this end we reanalyzed public expression data. To describe this collection of networks we introduced concepts of 'pan-network' and 'core-network' representing union and intersection between a sizeable fractions of i

SUBMITTER: He F 

PROVIDER: S-EPMC5159811 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature