Genomic Disparities in Breast Cancer Among Latinas.

ABSTRACT:

Background

Breast cancer is the most common cancer diagnosed among Latinas in the United States and the leading cause of cancer-related death among this population. Latinas tend to be diagnosed at a later stage and have worse prognostic features than their non-Hispanic white counterparts. Genetic and genomic factors may contribute to observed breast cancer health disparities in Latinas.

Methods

We provide a landscape of our current understanding and the existing gaps that need to be filled across the cancer prevention and control continuum.

Results

We summarize available data on mutations in high and moderate penetrance genes for inherited risk of breast cancer and the associated literature on disparities in awareness of and uptake of genetic counseling and testing in

SUBMITTER: Lynce F 

PROVIDER: S-EPMC5160045 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature