Topical NSAIDs for chronic musculoskeletal pain: systematic review and meta-analysis.

ABSTRACT:

Unlabelled

: A previous systematic review reported that topical NSAIDs were effective in relieving pain in chronic conditions like osteoarthritis and tendinitis. More trials, a better understanding of trial quality and bias, and a reclassification of certain drugs necessitate a new review.

Methods

Studies were identified by searching electronic databases, and writing to manufacturers. We identified randomised, double blind trials comparing topical NSAID with either placebo or another active treatment, in adults with chronic pain. The primary outcome was a reduction in pain of approximately 50% at two weeks, and secondary outcomes were local and systemic adverse events and adverse event-related withdrawals. Relative benefit and number-needed-to-treat (NNT), and relative harm

SUBMITTER: Mason L 

PROVIDER: S-EPMC516039 | biostudies-literature | 2004 Aug

REPOSITORIES: biostudies-literature