Effect of Public Deliberation on Attitudes toward Return of Secondary Results in Genomic Sequencing.

ABSTRACT: The increased use of genomic sequencing in clinical diagnostics and therapeutics makes imperative the development of guidelines and policies about how to handle secondary findings. For reasons both practical and ethical, the creation of these guidelines must take into consideration the informed opinions of the lay public. As part of a larger Clinical Sequencing Exploratory Research (CSER) consortium project, we organized a deliberative democracy (DD) session that engaged 66 participants in dialogue about the benefits and risks associated with the return of secondary findings from clinical genomic sequencing. Participants were educated about the scientific and ethical aspects of the disclosure of secondary findings by experts in medical genetics and bioethics, and then engaged in facilitate

SUBMITTER: Gornick MC 

PROVIDER: S-EPMC5161735 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature