Characterization of three new competence-regulated operons in Haemophilus influenzae.

ABSTRACT: Haemophilus influenzae is one of a growing number of bacteria in which the natural ability to uptake exogenous DNA for potential genomic transformation has been recognized. To date, several operons involved in transformation in this organism have been described. These operons are characterized by a conserved 22-bp regulatory element upstream of the first gene and are induced coincident with transfer from rich to nutrient-depleted media. The previously identified operons comprised genes encoding proteins that include members of the type II secretion system and type IV pili, shown to be essential for transformation in other bacteria, and other proteins previously identified as required for transformation in H. influenzae. In the present study, three novel competence operons were identified b

SUBMITTER: VanWagoner TM 

PROVIDER: S-EPMC516621 | biostudies-literature | 2004 Oct

REPOSITORIES: biostudies-literature