Different mechanosensory stimulations of the lower back elicit specific changes in hemodynamics and oxygenation in cortical sensorimotor areas-A fNIRS study.

ABSTRACT:

Background and objectives

This study aimed at investigating the feasibility of functional near-infrared spectroscopy (fNIRS) to measure changes in cerebral hemodynamics and oxygenation evoked by painful and nonpainful mechanosensory stimulation on the lower back. The main objectives were to investigate whether cortical activity can be (1) detected using functional fNIRS, and (2) if it is possible to distinguish between painful and nonpainful pressure as well as a tactile brushing stimulus based on relative changes in oxy- and deoxyhemoglobin ([O₂Hb] and [HHb]).

Methods

Twenty right-handed subjects (33.5 ± 10.7 years; range 20-61 years; 8 women) participated in the study. Painful and nonpainful pressure stimulation was exerted with a thumb grip perpendicularly to t

SUBMITTER: Vrana A 

PROVIDER: S-EPMC5167005 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature