Effect of peripheral arterial disease on the onset of lactate threshold during cardiopulmonary exercise test: study protocol.

ABSTRACT:

Introduction

Cardiopulmonary exercise test (CPET) is widely used in preoperative assessment and cardiopulmonary rehabilitation. The effect of peripheral arterial disease (PAD) on oxygen delivery (VO₂) measured by CPET is not known. The aim of this study was to investigate the effect of PAD on VO₂ measurements during CPET.

Methods and analysis

We designed a prospective cohort study, which will recruit 30 patients with PAD, who will undergo CPET before and after treatment of iliofemoral occlusive arterial disease. The main outcome measure is the difference in VO₂ at the lactate threshold (LT) between the 2 CPETs. The secondary outcome measure is the relationship between change in VO₂ at the LT and peak exercise pretreatment and post-

SUBMITTER: Key A 

PROVIDER: S-EPMC5168619 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature