Association of low-density lipoprotein cholesterol within the normal range and NAFLD in the non-obese Chinese population: a cross-sectional and longitudinal study.

ABSTRACT:

Objectives

The relationship between normal low-density lipoprotein cholesterol (LDL-c) levels and non-alcoholic fatty liver disease (NAFLD) in non-obese individuals remains unclear. We aimed to investigate the precise prevalence and incidence of NAFLD within the normal LDL-c range in non-obese individuals.

Design

Cross-sectional and longitudinal study.

Setting

Wenzhou Medical Center of Wenzhou People's Hospital from 2010 to 2014.

Participants

183 903 non-obese individuals were enrolled from a cross-sectional population, and a total of 16 173 initially NAFLD-free non-obese individuals were included who completed a 5-year follow-up examination in the longitudinal population.

Results

In our study, NAFLD was defined by ultrasonographic detection of steatosis

SUBMITTER: Sun DQ 

PROVIDER: S-EPMC5168665 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature