Effects of continuous positive airway pressure on energy intake in obstructive sleep apnea: A pilot sham-controlled study.

ABSTRACT: Obesity is among the leading risk factors for obstructive sleep apnea (OSA). A reciprocal relationship between obesity and OSA has been proposed, which may be due to excessive food intake. We conducted a pilot study to test the effects of continuous positive airway pressure (CPAP) on energy intake (EI) in OSA patients using a sham-controlled crossover design. In-laboratory total daily EI was assessed after 2mo of active and sham CPAP. Four men were enrolled (age±SEM: 51.8±2.1y; body mass index: 31.5±1.5kg/m²). All received active treatment first. Meals (breakfast, lunch, dinner, snack) were served in excess portions at fixed times and additional palatable snacks were freely available throughout the day. Total EI was lower after active (3744±511kcal/d) vs. sham (4030±456kcal/d) C

SUBMITTER: Shechter A 

PROVIDER: S-EPMC5172396 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature