Effectiveness of Teriparatide on Fracture Healing: A Systematic Review and Meta-Analysis.

ABSTRACT:

Purpose

Nowadays, the efficacy of teriparatide in treating osteoporosis was widely accepted, but the discussion about using teriparatide to enhance fracture healing hasn't come to an agreement. This meta-analysis was conducted to evaluate the effectiveness of teriparatide for fracture healing.

Methods

We searched PubMed, the Cochrane Library, and Embase in August 2016 for randomized controlled trials (RCTs) which concerned the treatment of teriparatide for fracture healing.

Results

Finally, a total of 380 patients were randomly assigned in the 5 trials included in this meta-analysis. There was a significant effectiveness with regards to function improvement in patients following fracture, however, there was no significant effectiveness with regards to time of radiogra

SUBMITTER: Shi Z 

PROVIDER: S-EPMC5173248 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature