Weight Change and Risk of Venous Thromboembolism: The Tromso Study.

ABSTRACT:

Background

Obesity is a major risk factor for venous thromboembolism (VTE), but it is unknown to what extent weight change over time affects VTE risk.

Aims

To investigate the association between weight change and risk of incident VTE in a population-based cohort with repeated measurements.

Methods

Participant data were collected from the Tromsø 3 (1986-87), 4 (1994-95), 5 (2000-01) and 6 (2007-08) surveys. Subjects who attended two subsequent or more surveys were included (n = 17802), and weight change between the surveys was calculated. Person-time at risk was accrued from the second of two subsequent vists until the next survey, the date of an incident VTE, migration, death or study end (December 31st 2012), whichever came first. Cox regression models were used to c

SUBMITTER: Horvei LD 

PROVIDER: S-EPMC5173365 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature