Hospital Variation in Time to Epinephrine for Nonshockable In-Hospital Cardiac Arrest.

ABSTRACT:

Background

For patients with in-hospital cardiac arrests attributable to nonshockable rhythms, delays in epinephrine administration beyond 5 minutes is associated with worse survival. However, the extent of hospital variation in delayed epinephrine administration and its effect on hospital-level outcomes is unknown.

Methods

Within Get With The Guidelines-Resuscitation, we identified 103 932 adult patients (≥18 years) at 548 hospitals with an in-hospital cardiac arrest attributable to a nonshockable rhythm who received at least 1 dose of epinephrine between 2000 and 2014. We constructed 2-level hierarchical regression models to quantify hospital variation in rates of delayed epinephrine administration (>5 minutes) and its association with hospital rates of survival to dischar

SUBMITTER: Khera R 

PROVIDER: S-EPMC5173427 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature