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Systematic review of the accuracy of antibody tests used to screen asymptomatic adults for hepatitis C infection.


ABSTRACT:

Background

Several expert groups, including the United States Preventive Services Task Force and the Canadian Task Force on Preventive Health Care, have recently examined or are currently examining whether primary care physicians should screen asymptomatic adults for hepatitis C virus (HCV) infection. To inform decision-making on HCV screening, we performed a systematic review of the accuracy of antibody tests compared with other immunoassays and RNA detection for screening asymptomatic adults for HCV infection in Canada.

Methods

MEDLINE and Embase databases were searched from 1990 to 2016; resulting citations were uploaded into DistillerSR and independently screened by 2 reviewers. Original research studies, systematic reviews and meta-analyses were eligible for inclusion.

SUBMITTER: Cadieux G 

PROVIDER: S-EPMC5173481 | biostudies-literature | 2016 Oct-Dec

REPOSITORIES: biostudies-literature