Fecal microbial transplant for the treatment of pediatric inflammatory bowel disease.

ABSTRACT: The role of fecal microbial transplant (FMT) in the treatment of pediatric gastrointestinal disease has become increasingly popular among pediatric practitioners, patients, and parents. The success of FMT for the treatment of recurrent Clostridium difficile infection (RCDI) has bolstered interest in its potential application to other disease states, such as inflammatory bowel disease (IBD). FMT has particular interest in pediatrics, given the concerns of patients and parents about rates of adverse events with existing therapeutic options, and the greater cumulative medication burden associated with childhood-onset disease. Published literature on the use of FMT in pediatrics is sparse. Only 45 pediatric patients treated for RCDI have been reported, and only 27 pediatric patients wit

SUBMITTER: Wang AY 

PROVIDER: S-EPMC5175243 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature