Impact of acute psychological stress on cardiovascular risk factors in face of insulin resistance.

ABSTRACT: Individuals with insulin resistance (IR) are at greater risk for cardiovascular disease (CVD). Psychological stress may contribute to develop CVD in IR, although mechanisms are poorly understood. Our aim was to test the hypothesis that individuals with IR have enhanced emotional and physiological responses to acute psychological stress, leading to increased CVD risk. Sixty participants were enrolled into the study, and classified into IR group (n = 31) and insulin sensitive group (n = 29) according to the Quantitative insulin sensitivity check index, which was calculated based on an oral glucose tolerance test. The Trier social stress test, a standardized experimental stress paradigm, was performed on each participant, and emotional and physiological responses were examined. Blood was coll

SUBMITTER: Jones KT 

PROVIDER: S-EPMC5175456 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature