Ictal EEG source imaging in presurgical evaluation: High agreement between analysis methods.

ABSTRACT:

Purpose

To determine the agreement between five different methods of ictal EEG source imaging, and to assess their accuracy in presurgical evaluation of patients with focal epilepsy. It was hypothesized that high agreement between methods was associated with higher localization-accuracy.

Methods

EEGs were recorded with a 64-electrode array. Thirty-eight seizures from 22 patients were analyzed using five different methods phase mapping, dipole fitting, CLARA, cortical-CLARA and minimum norm. Localization accuracy was determined at sub-lobar level. Reference standard was the final decision of the multidisciplinary epilepsy surgery team, and, for the operated patients, outcome one year after surgery.

Results

Agreement between all methods was obtained in 13 patients (59%)

SUBMITTER: Beniczky S 

PROVIDER: S-EPMC5176190 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature