Depression at antiretroviral therapy initiation and clinical outcomes among a cohort of Tanzanian women living with HIV.

ABSTRACT:

Objective

The objective of the study was to assess the relationship of depression at antiretroviral therapy (ART) initiation with mortality and clinical outcomes among Tanzanian women living with HIV.

Design

We conducted a prospective cohort study of 1487 women who initiated ART in Dar es Salaam, Tanzania.

Methods

Symptoms of depression and anxiety were assessed using a Tanzanian-adapted and validated version of the Hopkins Symptom Checklist. Participants attended monthly clinic visits during the first 2 years of ART and CD4 T-cell counts were assessed every 4 months. Proportional hazard models were used to assess the relationship of depression with mortality and clinical outcomes.

Results

Symptoms consistent with depression were prevalent among 57.8% of women

SUBMITTER: Sudfeld CR 

PROVIDER: S-EPMC5177498 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature