Outcome reporting bias in randomized trials funded by the Canadian Institutes of Health Research.

ABSTRACT:

Background

The reporting of outcomes within published randomized trials has previously been shown to be incomplete, biased and inconsistent with study protocols. We sought to determine whether outcome reporting bias would be present in a cohort of government-funded trials subjected to rigorous peer review.

Methods

We compared protocols for randomized trials approved for funding by the Canadian Institutes of Health Research (formerly the Medical Research Council of Canada) from 1990 to 1998 with subsequent reports of the trials identified in journal publications. Characteristics of reported and unreported outcomes were recorded from the protocols and publications. Incompletely reported outcomes were defined as those with insufficient data provided in publications for inclusio

SUBMITTER: Chan AW 

PROVIDER: S-EPMC517858 | biostudies-literature | 2004 Sep

REPOSITORIES: biostudies-literature