Prediction of Coronary Artery Disease Extent and Severity Using Pulse Wave Velocity.

ABSTRACT:

Background

Pulse-wave velocity (PWV) measures aortic stiffness. It is an independent predictor of cardiovascular events and mortality, yet there is paucity in the literature on its association with the severity and extent of coronary artery disease (CAD).

Methods

To examine the utility of PWV in predicting CAD burden in men and women the PWV was determined in 344 patients (Men = 266, Women = 78) presenting for invasive coronary angiography for the assessment of suspected CAD. Pearson correlations and multivariate analysis were used to evaluate the relationship between these coronary scores, PWV and traditional cardiovascular risk factors.

Results

Compared to men, women with chest pain had lower mean Extent scores (19.2 vs. 35.6; p = 0.0001) and Gensini scores (23.6 vs

SUBMITTER: Chiha J 

PROVIDER: S-EPMC5179020 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature