Evidence for Weakened Intercellular Coupling in the Mammalian Circadian Clock under Long Photoperiod.

ABSTRACT: For animals living in temperate latitudes, seasonal changes in day length are an important cue for adaptations of their physiology and behavior to the altered environmental conditions. The suprachiasmatic nucleus (SCN) is known as the central circadian clock in mammals, but may also play an important role in adaptations to different photoperiods. The SCN receives direct light input from the retina and is able to encode day-length by approximating the waveform of the electrical activity rhythm to the duration of daylight. Changing the overall waveform requires a reorganization of the neuronal network within the SCN with a change in the degree of synchrony between the neurons; however, the underlying mechanisms are yet unknown. In the present study we used PER2::LUC bioluminescence imaging i

SUBMITTER: Buijink MR 

PROVIDER: S-EPMC5179103 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature