Is Adjuvant Cellular Immunotherapy Essential after TACE-Predominant Minimally-Invasive Treatment for Hepatocellular Carcinoma? A Systematic Meta-Analysis of Studies Including 1774 Patients.

ABSTRACT:

Purpose

Cellular immunotherapy has appeared to be a promising modality for the treatment of malignant tumor. The objective of this study was to evaluate the efficacy of cellular immunotherapy combined with minimally invasive therapy.

Methods

We searched PubMed, Web of Science and The Cochrane Library through March 2016 for relevant studies. Short-term efficacy (the disease control rate, the control rate of quality life and the AFP descent rate) and long-term efficacy (overall survival (OS) and progression-free survival (PFS) rate) were compared as the major outcome measures. The meta-analysis was performed using Review Manager 5.3.

Results

A total of 1174 references in 3 databases were found of which 19 individual studies with 1774 HCC patients enrolled in this meta-a

SUBMITTER: Ding M 

PROVIDER: S-EPMC5179243 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature