Mexican-American Dementia Nomogram: Development of a Dementia Risk Index for Mexican-American Older Adults.

ABSTRACT: OBJECTIVESTo create a risk index (Mexican American Dementia Nomogram (MADeN)) that predicts dementia over a 10-year period for Mexican Americans aged 65 and older.DESIGNRetrospective cohort study with longitudinal analysis.SETTINGTexas, New Mexico, Colorado, Arizona, and California.PARTICIPANTSHispanic Established Populations for the Epidemiologic Study of the Elderly (H-EPESE) participants (n = 1,739).MEASUREMENTSDementia was defined as a decline of three or more points per year on the Mini-Mental State Examination and inability to perform one or more daily activities. Candidate risk factors included demographic characteristics, measures of social engagement, self-reported health conditions, ability to perform daily activities, and physical activity.RESULTSThe MADeN comprised the following risk factors: age, sex, education, not having friends to count on, not attending community events, diabetes mellitus, feeling the blues, pain, impairment in instrumental activities of daily living, and unable to walk a half-mile. The area under the receiver operating characteristic curve was 0.74 (95% confidence interval (CI) = 0.70-0.78) and a score of 16 points or higher had a sensitivity of 0.65 (95% CI = 0.59-0.72) and specificity of 0.70 (95% CI = 0.67-0.73) in predicting dementia.CONCLUSIONThe MADeN was able to predict dementia in a population of older Mexican-American adults with moderate accuracy. It has the potential to identify older Mexican-American adults who may benefit from interventions to reduce dementia risk and to educate this population about risk factors for dementia.

SUBMITTER: Downer B 

PROVIDER: S-EPMC5180363 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature