Simultaneous noninvasive recording of skin sympathetic nerve activity and electrocardiogram.

ABSTRACT:

Background

Sympathetic nerve activity is important to cardiac arrhythmogenesis.

Objective

The purpose of this study was to develop a method for simultaneous noninvasive recording of skin sympathetic nerve activity (SKNA) and electrocardiogram (ECG) using conventional ECG electrodes. This method (neuECG) can be used to adequately estimate sympathetic tone.

Methods

We recorded neuECG signals from the skin of 56 human subjects. The signals were low-pass filtered to show the ECG and high-pass filtered to show nerve activity. Protocol 1 included 12 healthy volunteers who underwent cold water pressor test and Valsalva maneuver. Protocol 2 included 19 inpatients with epilepsy but without known heart diseases monitored for 24 hours. Protocol 3 included 22 patients admitted wi

SUBMITTER: Doytchinova A 

PROVIDER: S-EPMC5182108 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature