Inverse association between carbohydrate consumption and plasma adropin concentrations in humans.

ABSTRACT:

Objective

The role of metabolic condition and diet in regulating circulating levels of adropin, a peptide hormone linked to cardiometabolic control, is not well understood. In this study, weight loss and diet effects on plasma adropin concentrations were examined.

Methods

This report includes data from (1) a weight loss trial, (2) an evaluation of acute exercise effects on mixed-meal (60% kcal from carbohydrates) tolerance test responses, and (3) a meta-analysis to determine normal fasting adropin concentrations.

Results

Distribution of plasma adropin concentrations exhibited positive skew and kurtosis. The effect of weight loss on plasma adropin concentrations was dependent on baseline plasma adropin concentrations, with an inverse association between baseline and a

SUBMITTER: Stevens JR 

PROVIDER: S-EPMC5184848 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature